Carbapenem Resistant Enterobacteriaceae at Hospital Nacional Mario Catarino Rivas during the First Semester of 2016

Abstract

Background: The noticeable increase of carbapenem resistant enterobacteriaceae (CRE) and its negative impact in health issues have generated worries and have motivated a national research of our epidemiology. Objective: the main aim of this study was to obtain the prevalence of CRE and the most frequent isolates sites at Hospital Nacional Mario Catarino Rivas (HNMCR), done from January 1st up to June 30th of 2016. Methodology: descriptive, transversal, prospective study. Data was obtai- ned from the daily microbiological registry of the Department of Microbiology at HNMCR. CRE was defined according Center for Disease Control and Prevention (CDC) standards using the sensibility parameters of the Clinical Laboratory Standards Institute (CLSI) M100 S24. Results: 696 enterobacteriaceae were reported of which 71 (10.2%) met the CDC phenotypic definition of which Klebsiella pneumoniae reported 21 (29.58%), Enterobacter aglomerans 20 (28.17%) and Escherichia coli 12 (16.9%). CRE were isolated in 4 (5.6%) patients in each of the following areas in the hospital: surgery emer- gency room, womens surgery ward, infants ward and women internal medicine ward, thus representing 27.65%. 15 (21.13%) CRE were isolated in April and 26 (36.6%) were isolated in urine cultures. Conclusions: Klebsiella pneumoniae was the most prevalent CRE in HNMCR. April presented the highest CRE reports. The isolates from urine cultures were the most frequently reported.

Keywords

Diagnostic, Enterobacteriaceae, Epidemiology, Microbiology